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[KO Validated] MLH1 Mouse mAb
[KO Validated] MLH1 Mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0499
Reactivity:Human
Applications:WB,ELISA
Modifcation:Unmodified
Source:Mouse
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20ul Size Available
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[KO Validated] MLH1 Mouse mAb

Immunohistochemistry analysis of paraffin-embedded Human Follicular lymphoma using human IgG (Fc) Mouse mAb (A21215) at dilution of 1:200 (40x lens). High pressure antigen retrieval performed with 0.01M Tris/EDTA Buffer (pH 9.0) prior to IHC staining.

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Product Details
Product Name
[KO Validated] MLH1 Mouse mAb
Description
The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC).
Catalog No
W0499
Reactivity
Human
Applications
WB, ELISA
Application Dilutions
WB,1:100 - 1:500 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Unmodified
Source
Mouse
Isotype
IgG1,Kappa
Immunogen
Recombinant protein of human MLH1.
Calculated MW (kDa)
85kDa
Observed MW (kDa)Gene Name
Refer to figuresMLH1
Other Name
FCC2; COCA2; HNPCC; MLH-1; hMLH1; HNPCC2; LYNCH2; MMRCS1; H1
Gene ID
4292
Human Swiss Prot
P40692
Formulation
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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